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Parasites and cancers: parasite antigens as possible targets for cancer immunotherapy

Damaged TECs promote inflammation and fibrosis through several mechanisms, including EMT, the release of pro-inflammatory factors, and the activation of signaling pathways, such as the TGF-1/Smad3 pathway ( 3.2.2 Ferroptosis-inflammation-fibrosis Ferroptosis not only directly affects the survival of renal TECs but also affects the inflammatory response by inducing macrophage polarization

Apart from this, some research studies have isolated the cDNA of cytotoxic proteins from traditional Chinese medicines, which were then used to transport these genes to malignant cells via a recombinant adeno-associated virus

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