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Description

The NIrp3 inflammasome: contributions to intestinal homeostasis

The compound itself is a modified version of the natural GLP-1 molecule

Similar to the APAP uptake rate, variation in the glucuronidation rate also increased the overall damage distribution for patients A (low overdose), B (medium overdose), C (mediumhigh overdose), and D (high overdose)

GO analysis delivered an enrichment of hypermethylated DMPs/genes, in biological processes involved in the regulation of cellular adhesion and signaling, including regulation of wound healing, spreading of epidermal cells (p=0.01), negative regulation of cell-substrate junction organization (p=0.03) and negative regulation of focal adhesion assembly (p=0.03) ( Figure 1E