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Beyond single-agent strategies, hydrogel platforms can be customized for combinatorial radiosensitization, integrating multiple agents that target complementary mechanisms of resistance [133]

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Additionally, integrating biomarkerguided patient stratification (e.g., based on mitochondrial function or NTFs receptor status) into trial design may help identify subgroups most likely to benefit from axistargeted therapies

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Eliminates toxins

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