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The researchers examined the impact of these interventions through a biochemical characterization of brain homogenates, quantifying oxidative and inflammatory markers such as lipid peroxides, glutathione (GSH), glutathione S-transferase (GST), 5-lipoxygenase (5-LOX), cyclooxygenase-2 (COX-2), leukotriene B4, prostaglandin E2, and ascorbic acid using spectrophotometric assays and ELISA

10.1161/STROKEAHA.116.015609 Summary Keywords CHAC1, CHAC2, glutathione, ferroptosis, cancer, BOTCH, endoplasmic reticulum stress Citation Schrder E, Jalilvand TV, Kahl J, Kaiser CS and Liebau E (2025) The strategic breakdown: CHAC enzymes as regulators of glutathione homeostasis and disease implications

In this work, we analyze by whole genome sequencing (WGS) 25 bacterial isolates of different enterobacterial species from untreated urban effluents of the northern area of Madrid (Spain), sampled between 2011 and 2013, as well as three clinical Citrobacter freundii isolates that caused a fatal outbreak in a tertiary hospital (Gmez-Gil et al., 2010) in the same catchment area

PubMed Central , Willard, Stacey S., and Shahriar Koochekpour