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Furthermore, several reports have indicated the therapeutic use of certain lipid or lipid precursor molecules that reduce LID in animal LID models, including plasmalogen precursors 22,23,24 , docosahexaenoic acid (DHA) 25,26,27 and endocannabinoids 28

[ 12 , 16 ] Researchers hypothesize that this mechanism could contribute to some of the sleep-related effects reported in early studies

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The gut mucosal response appears consistent across sex and hormonal status, making gut lining indications a strong match for female patients who are dealing with the GI consequences of hormonal fluctuation, antibiotic cycles, or inflammatory conditions