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Reduced FH expression leads to the accumulation of HIF-1 699 and high levels of fumarate, a cancer-associated oncometabolite, often resulting in cellular dysfunction in SDH- or FH-deficient cells

If this is the case for you, the next step would be comprehensive stool testing and treating the root cause of the digestion/absorption issues

Mason OU, Han J, Woyke T, Jansson JK (2014) Single-cell genomics reveals features of a Colwellia species that was dominant during the deepwater horizon oil spill