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This metabolic association between astrocytes and neurons was shown to be disrupted by the apoE4 isoform [52, 53]

Measurement of the TNF- and IL-1 by ELISA The TNF- and IL-1 levels in the perihematomal were determined using ELISA kits (USCN Life Science Inc., Wuhan, China) according to the manufacturers instructions

d'autre part, il contribue la stabilit de la membrane des globules rouges, empchant l'hmoglobine d'tre oxyde en mthmoglobine et de perdre ainsi sa capacit de transport de l'oxygne