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doi: 10.1016/j.bbi.2020.04.040

These findings pave the way to harnessing the spatiotemporal modulation of G s signaling and its untapped therapeutic potential

r in each case 1 Independently is hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, halogen, -OR A1 -N(R A1 ) 2 -SR A1 (ii) a Wherein R is A1 Independently at each occurrence is hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted carbocyclyl, optionally substituted heterocyclyl, optionally substituted aryl, optionally substituted heteroaryl, oxygen protecting group (when attached to an oxygen atom), sulfur protecting group (when attached to a sulfur atom), nitrogen protecting group (when attached to a nitrogen atom), or both R A1 The groups join to form an optionally substituted heterocyclic ring or an optionally substituted heteroaryl ring

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