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Complement activation is a critical pathway in the pathogenesis of inflammatory skin diseases such as acne, yet its specific mechanisms of action and key regulatory factors remain to be elucidated

Penetrating 10 layers deep into the skin, its lightweight, non-sticky texture ensures swift action in reducing pigmentation

Works to neutralize free radicals in the body causing oxidative stress to the cellular structure

These interventions should be individualized and biomarker-guided (e.g., endothelial function, Prx redox state, GSH/GSSG, F 2 -isoprostanes, LIP assays) and titrated to preserve beneficial H 2 O 2 -based signalling while preventing convergence onto ONOO , hydroxyl-radical formation and runaway lipid peroxidation (Frijhoff et al