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In addition, lactate accumulation can activate gluconeogenesis in liver and skeletal muscle cells, through which lactate is converted to glucose and released into the blood to drive additional glucose consumption during energy expenditure 28

Mendelian randomization analyses, which consider the environmental and lifestyle risk factors obtained from the literature, have indicated that high cholesterol levels play a causal role, again suggesting the importance of lipid metabolism [97]

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Your body produces its own glutathione, but several factors can deplete these stores