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In the screening phase, the main limitations occurred in the frailty assessment tools

2.8 Assessment of organ-specific physiological parameters 2.8.1 Liver-specific injury markers For the 3D liver microtissue models, hepatotoxicity and cellular damage were assessed through the analysis of culture supernatants

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[72% vs 56%] (24) Arlington test The clinician grasps the supine patients calf and ankle and moves their lower limb into a FABER position (Flexion, Abduction, and External Rotation)