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While sub-threshold concentrations of each ligand alone did not alter basal spinogenesis, combined sub-threshold concentrations of 30 " M Dihexa and 2.5 ng/ml HGF or 10 " 13 M Nlel -AnglV and 2.5 ng/ml of HGF produced a near ceiling effect, similar to biological responsive doses of each ligand alone (Figure 1 1 A and B)

As oral GSH precursors both N-acetylcysteine [95] and alpha-lipoic acid are appropriate

Biogenic amines and the states of sleep

This approach addresses potential challenges such as apoptosis in the center of organoids and enhances the physiological relevance of the model for studying endometrial function