Cell Death Differ
In conclusion, this study shows that CPT1A P479L mutant mice are resistant to rotenone-induced PD, and that inhibition of CPT1 using etomoxir restores some aspects of motor and non-motor function, LDL-c/HDL-c ratio, TH levels, possibly decreases -syn deposition and reduces gene expression of reactive microglia/macrophage markers in the midbrain in C57Bl/6J mice exposed to rotenone
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