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Apoptosis 28, 958976

This study demonstrates that MITOL-mediated K63-linked polyubiquitination at K68 of HMOX2 plays a crucial role in maintaining mitochondrial iron homeostasis

If blood loss continues long enough that body iron stores are depleted and absorption of dietary iron is inadequate to meet the demand created by increased red blood cell production, then iron becomes a limiting factor and effective erythropoiesis is decreased

More recently macrophages were isolated from a human buffy coat fraction after sequential removal of PMNs and lymphocytes using iodixanol density barriers and platelets by differential centrifugation [26]