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however, genetics, cytokines, growth factors, hormones, such as estrogens and progesterone and/or their respective receptors, environmental and epigenetics, and the excessive synthesis of extracellular matrix (ECM), have been associated with the pathogenesis of UF ( Although hysterectomy is the common and definitive treatment for UF, it is associated with several downsides, namely, the removal of the uterus and infertility

doi: 10.1371/journal.pone.0149461

However, the large FAR of 0.54 reveals a pronounced tendency to overestimate warm-cloud occurrence