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A separate group of age-matched young controls (3 months old) was generated by purchasing 10-week-old mice and acclimating them for 2 weeks prior to sacrifice

doi: 10.3389/fimmu.2023.1109122 80 LeeSYooICheonYChoiEKimSKaH

The control variables included (1) number of years from the first-ever schizophrenia diagnosis date in Medicare claims (see Supplementary Methods) until the starting date of each subperiod, (2) number of inpatient stays or emergency room visits with a diagnosis of schizophrenia in the first or second position on the claim within 3 months before the starting date of a subperiod, and (3) temporal order of exposure (i.e., number of treatments used before this subperiod)

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