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RGD-GHK significantly promoted the mRNA level of loricrin (LOR) and filaggrin (FLG), which were associated with a marked reduction in the damaged skin barrier

It was speculated then that an increase of the threshold for voltage activation by high vacuolar Na + can be a mechanism for the prevention of a Na + leak from the vacuole at salt stress (Ivashikina & Hedrich, Reference Ivashikina and Hedrich2005)