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Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation

Chronic hyperglycemia is a basic characteristic of diabetes and a major causative factor of various macrovascular and microvascular complications, including diabetic encephalopathy

After removing duplicates, reviews, editorials, and studies that did not meet basic methodological standards, 36 remained

Interestingly, many of the hub targets have been reported to be involved in cell proliferation, tumorigenicity, and other biological functions, and we will explore these further in the following discussion section