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SKU: 378370332
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Description

Tcr-triggered extracellular superoxide production is not required for T-cell activation

Rac1 can bind to WRC, inducing a conformational change that promotes the activity of the Arp2/3 complex, leading to F-actin nucleation and lamellipodia formation

Furthermore, variants in COL3A1 , such as the p.Gly637Ser mutation, have been linked to collagen synthesis abnormalities in a single family with the autosomal dominant hEDS phenotype that was identified which led to reduced collagen secretion and the over-modification of collagen [5,73]