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10.1152/japplphysiol.00371.2003 108

If the Phase 2a results hold, retatrutide could become the first truly effective pharmaceutical treatment for this condition

[187b] These findings were corroborated in vitro by Brotherton and colleagues, [189] whereby soluble misfolded SOD1 was toxic to cultured CHO cells and increasing aggregated SOD1 solubility enhanced cellular toxicity