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Semaglutide use: Semaglutide itself slows gastric emptying, which may indirectly impair your bodys ability to absorb vitamin B12, leading to a vitamin B12 deficiency

This product may contain aluminum, which may accumulate to toxic levels in patients with renal dysfunction or during high-dose or long-term treatment

The following literature search used the terms (including closely related words and synonyms): metformin combined with microbiome and/or Vitamins A, C, D, E, B 1 , B 2 , B 3 , B 5, B 6 , B 12 , and folic acid, iron, magnesium, selenium, zinc, H 2 RAs, PPIs and polypharmacy

doi: 10.1080/10715762.2022.2163244 221 ShenYWenLZhangRWeiZShiNXiongQet al