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doi:10.1056/NEJMoa2215024 Lincoff AM, Brown-Frandsen K, Colhoun HM, et al

The fluorescence of A was significantly lower in GO + amlodipine (36%), GO + aminoguanidine (36%), and GO + NAC (49%) than in GO

We were able to resolve high-resolution ligand-bound structures for analogs 43 (ID: pdb_000013CV, 1.95 ), 53 (ID: pdb_000013CW, 2.48 ), 60 (ID: pdb_000013DF, 1.84 ), and 69 (ID: pdb_000035YH, 2.60 ) bound to UCHL3 ( Figure 5 , ligand density in Figure S1 and crystallographic data statistics in Table S1 S3 )