glutathione synthetase deficiency wiki The involvement of the Stat1/Nrf2

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Figure 2 3.2 B cell metabolism supports autoantibody production and intrarenal pathogenesis in lupus nephritis B cells drive SLE pathogenesis by differentiating into autoreactive plasma cells that produce pathogenic autoantibodies, acting as antigen-presenting cells to activate autoreactive T cells, and secreting pro-inflammatory cytokines, thereby collectively promoting immune complex deposition, end-organ damage, and systemic autoimmunity (112)

On an Autoxidisable Constituent of the Cell

DA GFP animals were kindly provided by Holger Reichardts laboratory