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Hay literatura humana Fase 2 dispersa, principalmente en pediatra (deficiencia de GH) y en adultos mayores, con endpoints variados y sin programa regulatorio moderno activo

Bats reconcile longevity with a high metabolic rate that results in a lifespan-energy expenditure that exceeds that of other mammals by as much as 2 times (Munshi-South and Wilkinson, 2010)

Salter and Fern (2005) have also reported that the activation of NMDA receptors results in the fast Ca 2+ -dependent morphological changes, which are manifested by detachment and disintegration of oligodendroglial processes and formation of swellings, and that blocking the NMDA receptors prevents injury to oligodendrocytic processes