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doi: 10.1002/path.5356 37 ChesnokovMSKhanIParkYEzellJMehtaGYousifAet al

Numerous animal models have been created to investigate AD, including vertebrate transgenic rodents, invertebrates such as zebrafish and Drosophila melanogaster , as well as naturally occurring models in NHPs and dogs (Figure 4)

Based on data obtained from these studies, the existence of a neurogenic inflammatory component in human airway diseases such as asthma and COPD seems very likely