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Symptoms of vitamin B6 deficiency include: acne, hair loss, normocytic anemia, loss of appetite, mouth ulcers, seizures, cognitive changes, rashes, cheilitis, a swollen tongue (glossitis), depression, nervousness, irritability, dizziness, numbness, pins and needles, electric shock sensations, sleepiness and fatigue, weakness, poor wound healing, joint pain, flaky skin, hearing problems, and growth retardation

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(ii) Ferroptosis may have occurred in certain anti-inflammatory immune cells in AT, which allows a large increase in pro-inflammatory immune cells, further causing systemic inflammation and insulin resistance, and ultimately leading to the development of obesity