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If the gene that converts SAH to homocysteine (AHCY) isnt fully supported, then it too can cause all sorts of problems

Dynamic structural remodelling of microglia in health and disease: a review of the models, the signals and the mechanisms

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Interestingly, SeCyS is efficiently methylated by certain plants, such as Brassica oleracea capitata (kale), Brassica juncea , and Allium tricoccum , which can accumulate high concentrations of Se in the form of selenomethionine (SeMet), resulting in increased levels of methylated metabolites [17, 18]