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MRS data analysis We applied a weighted combination of receiver channels, followed by motion corruption average removal, spectrum registration for frequency and phase drift correction, and pre-subtraction sub-spectral alignment in MATLAB 2019a (The Mathworks, Natick, MA, USA) using the FID-A toolkit before signal averaging and data analysis 56

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Relative intensities of the serum glutathione levels in young ( n = 4) and old ( n = 4) mice as determined by LC-MS analysis ( B )