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We then pre-incubated early ring-stage artemisinin resistant and sensitive parasites with BSO for 1 h prior to pulse treatment with 700 nM of DHA for 6 h and measured survival, analogous to the standard in vitro Ring-stage Survival Assay (RSA) for artemisinin resistance

For example, ROS produced by macrophages can induce the generation of Tregs [238], while mice lacking neutrophil cytosolic factor 1, even with low ROS levels, have more responsive Tregs than wild-type mice [168]

It is also noteworthy that metabolic dysfunction in CD8+ T cells, driven by the immunosuppressive microenvironment of chronic lymphocytic leukaemia (CLL), contributes to CAR-T therapy resistance (Van Bruggen et al, 2019)

Regulation of shivering and non-shivering heat production during acclimation of rats