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MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals

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These GH levels result in an often severe state of catabolism, with significant proteolysis and lipolysis

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Here, we used single-cell RNA sequencing (scRNA-seq) to provide a global description of the dynamic changes in immune cells after anti-TNF- therapy in responders and non-responders

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Total scores can range from a low of 15 to a high of 60

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