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doi: 10.1093/ijnp/pyy062 182 ZhangJLuoWHuangPPengLHuangQ

reported a modified grading system for the severity of CRS regardless of the inciting agent, which defined mild, moderate, severe, life-threatening symptoms, and even death

Oberdrster, E., Rittschof, D

Figure 3 2.1.1 Impact of dysregulation in gliomas One key regulatory step in the kynurenine pathway is the uptake of tryptophan and kynurenine (KYN) via transporters such as L-type amino acid transporter(LAT1) and ASCT2, which are often overexpressed in glioma