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The benefit of the micro-Matrix cassette (used in this study) is that, up to 24 different conditions can be tested at any time since each cassette house can be inoculated with faecal slurry and maintained under physiological conditions [87]

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This oxidative injury disrupts endothelial nitric oxide synthase (eNOS) function, reduces nitric oxide (NO) bioavailability, and promotes vascular stiffnessan early mechanistic link between redox imbalance and endothelial dysfunction

In univariate analysis, neither LPCR nor core volume was significantly associated with clinical outcome at 90 days