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In vitro studies on mouse macrophages also demonstrated the ability of 6-gingerol to inhibit NO and PGE2 production (62)

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Since Ser can enter mitochondria and contribute to the reduction of NADP + to NADPH through 5,10-methylenetetrahydrofolate, we speculate that SAAR induces serinogenesis to maintain the mitochondrial milieu in a reduced state and that its effect on glyceroneogenesis is a collateral health benefit

A 2017 review published in the International Journal of Molecular Sciences has found that nattokinase may be a beneficial antithrombotic agent to reduce the risk of cardiovascular disease ( 47 )