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While generally well-tolerated, side effects can include site irritation, temporary water retention, or flushing

Recently, they have surged in popularity again thanks to TikTok, skin cycling routines, and skin longevity conversations that frame copper peptides as a powerful anti-aging ingredient capable of repairing skin on a cellular level

The cyclization to a hemiacetal is likely to take place through the incorporation of an oxygen function into the C-8 position of secologanin ( 27 ) derived from loganin ( 1 ) to generate further iridoid derivatives (Inouye et al., 1996)

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