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Acknowledgements We would like to thank Bruce Wolffenbuttel and Andrew McCaddon for their advice and assistance of this perspective

Rinalducci S, Ferru E, Blasi B, Turrini F, Zolla L

Recent work shows that PIF4 can phase separate with JASMONATE ZIM-domain protein 3 (JAZ3), which restricts PIF4s DNA-binding and transcriptional activation activities 58