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[DOI] [PMC free article] [PubMed] [Google Scholar] 76.Hill A.J., Jones N.A., Smith I., Hill C.L., Williams C.M., Stephens G.J., Whalley B.J

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Despite the established efficacy of sorafenib and regorafenib in advanced HCC, resistance frequently develops with prolonged use, adversely influencing the subsequent course of the disease [88]