melanotic macuole Labial macule image Labial melanotic macule. B). Increased

Stable in size and colour once formed

occasionally hard Maybe multifocal, usually when malignant MICROSCOPIC PATHOLOGY Histologic Features Melanotic schwannoma High cellularity, lobules and fascicles Spindle to epithelioid cells Eosinophilic to amphophilic cytoplasm Clear cells occasional Occasional multinucleation Variable pigmentation Nuclear/cytoplasmic pseudoinclusions Pigmentation variable or patchy Thin-walled vessels Scan often incomplete collagenous capsule Palisading, Verocay bodies, microcysts (very uncommon) Melanophages frequent and most pigmented of cells Benign Delicate chromatin and small nucleoli Rare mitoses Malignant Vesicular nuclei and coarse chromatin Stay updated, free articles

There are two different types of melanotan: melanotan 1 and Melanotan 2

J Urol 2005 Jun;173(6):1958-1965