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(4) An increased prevalence of depression is documented among patients with pediatric TT [336], especially in adolescents, who often need psychological support, due to the difficulty in expressing discomfort or addressing concerns with both family members and doctors [337]

Underlying deficiency correction : When severe B12 deficiency is corrected, some patients experience temporary neuropsychiatric symptoms as nerve function recoversa phenomenon sometimes called 'unmasking' of symptoms