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Description

Metallothionein shows an age-related decrease in human macular retinal pigment epithelium

Experimental design The experiment consisted of two treatment groups: a distilled water control (CK) and a copper stress treatment (Cu)

Furthermore, co-treatment with mitochondrially specific antioxidants including MitoQ, Trolox and Mito-Tempo have been demonstrated to abrogate GA-induced cognitive impairments in mice, potentially linking excessive mitochondrial ROS to PAN (13, 14, 70, 112)