oxidationo of glutathione The redox cycle, demonstrating the inter-conversion quality raw materials for production of classical and novel therapies Modelling changes in glutathione homeostasis

FeRD is highly prevalent among hospitalized COVID-19 patients and this clinical condition may continue for weeks or even months in PASC patients

(2021) showed that RIPK3 inhibits nuclear translocation of TFEB leading to lysosome dysfunction and impairment of autophagic degradation during AKI

In addition to the findings with ASMase knockout mice, which models the lysosomal storage disorder NiemannPick type A disease, inhibition of glucocerebrosidase in hepatocytes by conduritol -epoxide, a cellular model of Gaucher disease that exhibits lysosomal cholesterol accumulation sensitizes to APAP-induced cell death (Teratani et al., 2017)

The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice