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IR likewise causes charged particles (electrons or ions) to traverse the cell and directly ionize DNA, causing double-strand breaks (DSB), which could be restored by homologous recombination (HR) and non-homologous end joining (NHEJ) mechanisms, or a base damage and single-strand breaks (SSB) repaired by BER and SSB repair mechanisms, respectively (Maier et al., 2016)

Evidence from animal models highlights the impact of testosterone depletion on mitochondrial function in AD

Epigenetic inactivation of SPINT2 is associated with tumor suppressive function in esophageal squamous cell carcinoma

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