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p = 0.003)

However, the pathogenesis of AD cannot be fully explained by the aggregation of A and tau proteins alone, and strategies to reduce the burden of A have not been effective in limiting disease progression (Morris et al

99 These findings place autophagy-lipophagy failure at the mechanistic core of MASLD pathogenesis

Previous studies have confirmed that aging is characterized primarily by low-grade chronic inflammation, upregulation of senescent cells, and oxidative stress [184]