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These findings suggest that the combination of small molecule NNMT inhibitors with other nutritional supplements, such as the precursors of NAD + , may have the potential to enhance the efficacy of treatment for MetS and minimize the side effects caused by high pharmacological dosages (Roberti et al., 2021)

10.1002/cjoc.20010191206 93 PengZ.ZhangC.YanL.ZhangY.YangZ.WangJ.et al (2020)

Furthermore, melatonin-induced changes in glycosaminoglycan production may impact the TM, which regulates IOP, potentially influencing the pathophysiology of POAG (81)

5.6 Cerebrovascular diseases Interestingly, several studies have reported promising effects of pepper family derivatives in case of ameliorating risk factors for cerebrovascular diseases and reversing the outcomes such as neural damage