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[ref] Related article : PAI-1 genetic variants MicroRNAs (miRNAs) are short strands of RNA that can bind to mRNA and prevent a gene from being expressed

Cell and Tissue Research, 2019

Vessel co-option is defined as a non-angiogenic process whereby tumor cells directly utilize the pre-existing vasculature of the non-malignant tissue as a supply of oxygen and nutrients, resulting in resistance to anti-angiogenic therapy [5]