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Introduction Recombinant human growth hormone (rhGH) replacement therapy has been shown to reverse several metabolic alterations associated with low serum GH level or GH deficiency, including increased visceral adipose tissue (VAT), altered lipid profile, and impaired physical performance [13]

For instance, Mn 2+ physiologically supports the catalytic activity of glutamine synthetase (GS) as an essential divalent metal cofactor, while excessive Mn exposure can toxicologically impair GS expression and/or activity and disrupt the broader glutamateglutamine (GluGln) cycling network, thereby increasing the glutamate burden and the risk of excitotoxicity 144,179

Consistency is everything here

It is not free copper floating through your bloodstream causing damage