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Researchers have also explored its influence on orexigenic signaling , hypothalamic-pituitary axis dynamics , and metabolic homeostasis making it a versatile compound for those investigating neuroendocrine and performance-related mechanisms

Baicalein can increase superoxide dismutase and glutathione peroxidase activities and downregulate malondialdehyde, thereby alleviating oxidative stress (102)

Sex differences in neural responses to stress and drug cues predicts future drug use in individuals with substance use disorder

Additional studies have shown that spinal fusion may result in degeneration of adjacent discs and lead to further discogenic pain, herniation, stenosis or spondylosis, suggesting that improvements in surgical interventions for back pain are necessary (Ghiselli et al., 2004)