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Drug Deliv Transl Res 12:615628

Three new pigment protein tyrosine phosphatases inhibitors from the insect parasite fungus Cordyceps gracilioides : terreusinone A, pinophilin C and cryptosporioptide A

Under nutrient deprivation, HCC cells activate ketolysis to maintain energy supply, suppressing AMPK activity and inhibiting Tregs for rapid energy acquisition, HCC cells produce lactate via the Warburg effect