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However, research remains inconclusive: synbiotics may restore gut health and improve cognition [88], potentially offering novel therapeutic strategies [89, 90], but efficacy may be compromised during antibiotic use or contribute to cognitive impairment [91]

For example, if an animal responded 2 out of 5 times, the animals has a 40% response rate

Hepatitis A virus is responsible for about 4% of cases

More interestingly, a few metabolites (e.g., plasma histidine, erythroid carnitine derivatives) were reported to exclusively differ in PO+ children, whereas similar levels were detected in control and PO subjects, thus suggesting that PO might play an important role in modulating these metabolic programming mechanisms