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These findings suggest that NLCs designed to bind vascular endothelial growth factor receptor-2 (VEGFR-2) might be useful in delivering DTX to the tumor vasculature and tumor cells [208]

Plasma pharmacokinetics and brain uptake of 2B3-101 and pegylated liposomal doxorubicin in healthy mice

doi: 10.1007/s13238-014-0077-5 146 XuX.XiaC.HuangY

It is well established that glucose uptake decreases upon detachment 17,18,19 , but the main energy substrates and corresponding metabolic pathways necessary for maintaining MIC stemness under stress and initiating metastasis still need to be determined