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Dopaminergic SN cells are usually pigmented with black neuromelanin, produced from of the autoxidation [57] or enzyme-mediated oxidation [58] of the cytoplasmic dopamine (DA) to DA-o-quinone, which then Polymerizes

It is studied for its potential to promote deep sleep, regulate circadian rhythms, and enhance restorative sleep cycles

Long-term potentiation (LTP), which Dihexa enhances, has been shown to stimulate proliferation of progenitor cells in the dentate gyrus and promote survival of newly born neurons, suggesting Dihexa may facilitate neural regeneration through multiple complementary mechanisms

Thus, it prevents the activation of pain and migraine networks in the brain, including disruption of CGRP activity , which has become a central focus in most of the new migraine medications on the market such as the gepants and CGRP monoclonal antibodies